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Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: the STEP 3 randomized clinical trial

The best injection sites for weight loss may differ between medications due to different absorption profiles

Both treatments are approved for weight loss and have shown promising results in clinical trials

[1] The once-weekly injectable formulation of semaglutide has shown remarkable results in clinical trials, demonstrating greater weight loss compared to placebo and other weight-loss medications

Participants received either a once-weekly 2.4 mg dose of semaglutide or placebo, along with regular lifestyle counseling focused on healthy eating and physical activity