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Cardiac-resident macrophages upregulate CCL24 during pressure overload-induced injury, and CCL24 binds to CCR3 to promote fibroblast proliferation via transforming growth factor- activation 39 , suggesting a plausible role in ovarian fibrosis although this has not yet been reported in the ovary

Inhibition of MEK1/2 increases AKT phosphorylation To test whether MEK inhibition can increase AKT phosphorylation to activate AKT, we knocked down MEK1 and MEK2 expressions with mek1 and mek2 siRNA, respectively

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