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475 Deletion of the ZIP2 gene notably intensified myocardial I/R injury, whereas upregulation of ZIP2 demonstrated the potential to mitigate I/R injury

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This supports the medication's appetite-suppressing effects and helps prevent dehydration

It activates GLP-1R (class B GPCR) to stimulate Gs-cAMP-PKA signaling in pancreatic beta cells for glucose-dependent insulin secretion, suppress appetite through hypothalamic GLP-1R activation, and slow gastric emptying via vagal pathways