If additional benefit is desired and tolerated, a dose of 15 mg once weekly may be considered, continuing at that level as appropriate
GLP-1 receptors in the VTA and NAc modulate dopaminergic, glutamatergic, and GABAergic neurotransmission, all three major neurotransmitter systems involved in addiction
One scenario thats quite conceivable, he said, is that someone who has obesity and doesnt have frequent menstrual periods starts one of these medicines, loses weight over several months and finds that theyre still not having regular periods only now it might be because youre pregnant. On top of that, Mounjaro and Zepbound have a warning in their prescribing information that they may render birth control pills less effective
Some people lose more, some less
If diarrhea persists beyond 4 weeks, contact your provider