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Other neuronal systems are also affected, resulting in non-motor symptoms including cognitive decline

Research shows that pairing these medications may produce additive effects on glucose control and appetite suppression, though individual responses vary based on genetics and metabolism

347 MiR-181a increases the abundance of beneficial bacteria, inhibits the expression of the inflammatory cytokines IL-6, TNF- and IL-1, upregulates the expression of claudin-1 and ZO-1, and improves intestinal barrier function by regulating the composition of the intestinal microbiota

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However, if communication between these providers is limited, treatment plans can become misaligned