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Mediation analyses suggested that these benefits arose from a combination of weight loss and direct improvements in sleep-disordered breathing metrics, including the ApneaHypopnea Index (AHI) and sleep apnea-specific hypoxic burden

Understanding Semaglutide Semaglutide is a medication that belongs to a class of drugs known as GLP-1 receptor agonists

These secondary effects, such as gut microbiome dysbiosis, reduced diversity, and barrier compromise, may offset the anti-inflammatory effects of these medications

Thus, it is crucial to elucidate the precise underlying molecular mechanisms mediating its development in order to find novel, efficacious and promising therapeutic modalities for OA