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The approval was supported by data from the Phase III ADRIATIC study, which according to an April 2024 readout hit its primary efficacy endpoints of overall survival and progression-free survival (PFS)

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High glucose-induced ROS accumulation is a critical regulator of ERK1/2-Akt-tuberin-mTOR signalling in RGC-5 cells

Int J Mol Sci 19(1): 26