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Effect of folic acid supplementation on the progression of carotid intima-media thickness: a meta-analysis of randomized controlled trials

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The impact on postprandial glucose-lowering of altering the timing of metformin administration in relation to meals has been poorly characterised, although an open-label pilot study in five metformin-treated type 2 diabetes patients was indicative of improved glucose-lowering, enhanced GLP-1 secretion and slowed gastric emptying when metformin (1000 mg) was administered 30 min before the meal rather than with the meal [24]

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(1987b) had to Figure 4 ] was similar to that observed by injecting or infusing [both right into the cervical vein and thus bypassing any potential effects of digestion and/or the interaction with sweet receptors in the gut] the same doses of glucose (150 mg/kg) body weight for injection and 20 mg/kg body weight/min for infusion), except that no hyperglycemia was observed with Acesulfame K (Loang