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Chen HL, Woo XB, Wang HS, Lin YJ, Luo HX, Chen YH, et al

35 In MASLD, insulin resistance in both liver and adipose tissue disrupts these pathways, exacerbating steatosis and inflammation

doi:10.1111/dth.14631

Endpoints frequently measured include the activity of alkaline phosphatase (ALP), an early marker of osteoblast differentiation, the expression of the master osteogenic transcription factor Runx2, and the deposition of a mineralized matrix, which can be visualized with Alizarin Red staining

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