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The long-lasting effects observed in these models suggest the potential for therapies that provide sustained benefits

The individuals sustained the weight loss for over two years

Diabetes causes leakage of the BBB through downregulation of tight junction proteins, resulting in impaired functioning of endothelial cells, pericytes, astrocytes, microglia, nerve/glial antigen 2-glia, and oligodendrocytes

Neuroprotective Effects: Some studies have indicated that BPC-157 could have neuroprotective benefits, helping to repair nerve damage and support overall neurological function

TB-500's systemic anti-inflammatory effects support gut healing alongside BPC-157's more direct gastric benefits