GLP-1 receptor agonist drugs were originally developed to improve blood sugar control in diabetic patients, but their widespread use expanded rapidly after studies showed they could also promote weight loss
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This concern is particularly relevant for patients with stricturing CD, in whom up to 50% develop fibrostenotic complications within 10 years of diagnosis (74)
Two years ago, Breen had a body mass index of 50 and an alcohol problem
[1] This central nervous system effect can amplify feelings of queasiness, especially during dose escalation phases