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In mitochondrial dysfunction, increased ROS levels further inhibit GPX4 activity, accelerate PUFA oxidation and ultimately induce ferroptosis (25-27)

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Presentation: Lyophilized powder (research use) Target: Nicotinamide Nmethyltransferase (NNMT) inhibitor Suggested Use: In vitro / preclinical workflows as defined by protocol Storage: Follow validated lab SOPs for smallmolecule lyophilizates 1

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Tau an inhibitor of deacetylase HDAC6 function