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Mutation of Arginine 130 to alanine resulted in complete loss of activity consistent with a role for Arginine 130 in stabilizing the strongly nucleophilic GSH thiolate required for catalysis

Mutt's laboratory's peptide production funded a great deal of his research activity (Jrnvall, Agerberth, Zasloff)

However, those with an unbalanced diet or without access to fresh fruits and vegetables may not

In addition, very few studies have been conducted in people with addictive disorders

The clinical and metabolic effects of rapid weight loss in obese pet cats and the influence of supplemental oral Lcarnitine. Journal of veterinary internal medicine 14.6 (2000): 598-608