Jang Won Son, Carel W le Roux, Matthias Blher, Michael A Nauck, Soo Lim Endocrine Reviews , First published online October 7, 2025, bnaf036 The approvals of semaglutide and tirzepatide have set new benchmarks in the treatment of type 2 diabetes and obesity

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Although cell function improves in T2D patients, treatment with liraglutide in T1D did not significantly change mean C-peptide concentration (5658)
The Phase 3 results are promising, but most of the programme is still running, and the long-term cardiovascular outcomes data wont be available until 2028 at the earliest