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Receptor Desensitization (Downregulation) With continued exposure to high levels of GLP-1 agonists, receptor sensitivity may decline

Ria Shirsolkar recommends pairing the medication with healthy lifestyle changes, including a balanced diet and regular physical activity

Dosing of levothyroxine often requires adjustment over time, and the transition period is when we are most likely to encounter signs of imbalance in either direction

Initially, GLP-1 medication was developed to treat type 2 diabetes and, although it is effective, other significant weight loss benefits were also found , leading to their use as a weight management tool

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