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(Some GLP-1 agonists have been around for nearly two decades.) A lot of people who experience the common side effects tend to feel better as they continue on the medications, not worse

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For patients seeking maximum cholesterol benefit, combining tirzepatide with ongoing dietary improvements and physical activity yields better outcomes than medication alone

This substantial placebo response underscores the influence of non-specific trial factors and clinical follow-up on subjective pain outcomes in this population