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According to the recommendations for the management of patients with PWS, physical exercise should be an important part of patients daily life and prescribed as a coadjutant treatment to GH therapy, in addition to caloric restriction [33]

Option B: Planned stop Some people can stop at their current dose with close monitoring

They augment glucose-dependent insulin production while inhibiting glucagon, hence enhancing glycaemic control without the danger of hypoglycaemia (Meloni et al

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