The next level of inquiry with a larger randomized, double blind, placebo controlled efficacy trial is warranted
Currently, the rapid rise in demand for nutraceutical products has been largely observed because of their therapeutic value in various diseases, such as diabetes, hypertension, arthritis, inflammatory bowel disease, the common cold, dyslipidemia, heart disease, and cancer
In these types of experiments there is an increased rate of pancreatic -cell apoptosis, reduced -cell proliferation, and reduced glucose-dependent insulin secretion
The NIH Office of Dietary Supplements, citing Institute of Medicine recommendations, advises that it is advisable for those older than 50 years to meet their RDA mainly by consuming foods fortified with vitamin B12 or a supplement containing vitamin B12. This recommendation reflects the fact that 10 to 30% of older adults lose the ability to efficiently absorb naturally occurring B12 from food
Its documented benefits include: Stimulation of fibroblast activity and extracellular matrix remodeling
