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NRF2 in Amyotrophic Lateral Sclerosis ALS is the most common motor neuron disease in adults and estimates have reported that 31,000 patients live with ALS in the US, where on average 5,000 new patients are diagnosed annually (Mehta et al., 2023)

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However, a few aspects regarding the relationship between selenium and OA remain controversial

Intracellular ROS production Intracellular reactive oxygen species (ROS) levels were measured in treated cells using the oxidant-sensitive probe 2,7dichlorofluorescein diacetate [H 2 DCFDA] 11