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10.1007/s40618-017-0792-x 89 KimY.YooS.LimB.HongJ

doi: 10.1016/j.chroma.2004.05.045

Nighttime leg cramps usually involve the calf muscles or the foot muscles

Peptide-based approaches tend to have more manageable side effect profiles with temporary adaptation periods, while other compound classes may have more immediate effects but also carry more significant long-term risks

When muscle is injured or mechanically stimulated, HGF is released and binds to c-met receptors on satellite cellsthe resident stem cells of skeletal muscleawakening them from a resting state, enabling them to proliferate, differentiate, and contribute to muscle fiber repair