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Pathophysiology and treatment of enteric hyperoxaluria

Further investigation demonstrated that lactate administration in mice induced hepcidin expression, leading to reduced FPN levels

Vitamin deficiencies do not directly cause localized dark spots on the lips

This action is reminiscent of dimethyl fumarate (DMF), an approved MS therapy, which also downregulates pro-inflammatory cytokines like IL-1 and TNF- through microglial modulation [87,88]