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Eli Lilly has stated it "remains confident in the differentiated benefits of tirzepatide." Facing generic competition, Novo Nordisk has taken several steps: Launch of rebranded versions In December 2025, Health Canada approved two Novo Nordisk rebranded versions on December 22: These are identical to the branded versions but come in different packaging

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For Fried criteria, the study used the cutoff points of hand grip and gait speed from the original study published by Fried et al 27 conducted on a Western population rather than Asian