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In addition, L-theanine (100 mg/kg) could effectively regulate the metabolism of glucose, lipids, and proteins in SD rats, and the main mechanism was that L-theanine could upregulate the mRNA expression of phosphofructokinase (PFK), carnitine palmitoyltransferase 1 (CPT1), insulin receptor (IR), insulin receptor substrate (IRS), and liver kinase B1 (LKB1), and enhance the phosphorylation of adenosine 5-monophosphate-activated protein kinase (AMPK) (79)