The combination of dehydration and electrolyte imbalance can worsen fatigue
[80] The trial reported cumulative occurrence of major adverse cardiovascular events, a primary end-point event of the trial, for 569 of the 8803 patients in the semaglutide group, which were 6.5% of the participants, and for 701 of the 8801 patients in the placebo group, which were 8% of the participants, showing relative 18.8% less major adverse cardiovascular events, such as death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke, occurring for participants who had received semaglutide in the trial relative to those who had received placebo over the course of around 48 months, or 34.213.7 months, which was the mean (SD) total duration of the participants in either group's exposure to the placebo or semaglutide during the trial
This does not mean these items must be avoided entirely, but many patients report needing smaller portions or slower eating paces to stay comfortable
I spent a lot of time researching zepbound versus wegovy for someone close to me, and the dual GIP and GLP-1 action with tirzepatide really does make a difference in how the body responds
Resistance training two to three times per week, even at moderate intensity, dramatically reduces lean mass loss during weight loss
