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Phage therapy targeting this bacterium effectively alleviated steatohepatitis, improved liver function, and reduced the expression of inflammatory cytokines and lipogenic genes in mouse models, without causing significant pathological changes in liver/kidney function or gut flora composition, proving its efficacy and safety

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There is clear evidence to illuminate that defective Ca 2+ channel function can lead to ASD with penetrance as high as 60-80%

In the early stage of the disease, mitophagy mostly acts as an adaptive compensatory mechanism to play a protective role, while with the progression of the disease to the late stage, the regulatory mechanism of mitophagy is disrupted, often showing a state of excessive activation, thereby aggravating tissue damage