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Similar alterations have been reproduced in animal models exposed to testosterone esters or nandrolone decanoate, in which mitochondrial dysfunction and caspase-mediated apoptosis occur within Leydig and Sertoli cells (79)

Other studies have noted similar benefits of metformin therapy (70,71)

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Potential Side Effects and Considerations Though GLP-1 drugs offer exciting potential, they also come with side effects to consider, including: Nausea or vomiting Gastrointestinal upset Potential risk of pancreatitis Mood changes or fatigue in some users Because these medications act on complex systems within the brain and body, you should only use them under close supervision from a qualified medical provider

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