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A similar model has previously been used in several species (11-14)

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Muranov KO, Ostrovsky MA

J Bone Miner Res 20:8187 Gilkes DM, Bajpai S, Wong CC, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL (2013) Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis