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GLP-1 medications slow gastric emptying and increase insulin secretion in response to food, helping regulate post-meal glucose spikes

Restless Legs Syndrome (RLS) : It can help reduce the uncomfortable sensations and urge to move the legs that characterize RLS

If a patient is already nauseated on tirzepatide and adds a peptide that may cause its own GI symptoms, the combined burden can push them off therapy entirely

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In a published phase 2 trial, participants on the highest dose lost roughly a quarter of their body weight over about a year among the largest average weight-loss results reported for any medication studied to date