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Evaluation of safety and effectiveness of NAD in different clinical conditions (systematic review)

According to the National Institutes of Health, though, at least 15% of adults have a vitamin B12 deficiency, and the number increases with age

The 30% reduction in total cholesterol observed in research studies indicates significant improvements in lipid metabolism

There is one open-label intravenous safety pilot in two healthy adults, who received single doses of 10 mg and 20 mg with no comparator, no blinding, and short-term observation limited to vital signs, self reported symptoms and labs across two days [4]