B12 in particular is important for healthy nervous system and brain function, among others
The provider matters more than the molecule: sterility, verified concentration, correct dosing, and supervision are what separate a clinical result from a gamble
Ensuring proper administration technique (IM IV slowly diluted) also helps minimize adverse effects like injection pain or vein irritation
Eur J Pharmacol 741:112123 Iversen TZ, Engell-Noerregaard L, Ellebaek E, Andersen R, Larsen SK, Bjoern J, Zeyher C, Gouttefangeas C, Thomsen BM et al (2014) Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase
They typically give mega-doses (10-25 mg) to help those with significant B12 deficiency symptoms