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Most of the longevity data comes from animal studies, laboratory models, or small observational research from a limited group of investigators

Hormones and all essential amino acids have substrate-specific transporters, although cationic amino acids (lysine and arginine) or large neutral ones (tryptophan, tyrosine) share a transporter system (cationic amino acid transporters 1 and 3 (CAT-1/3)

doi: 10.1007/s12072-020-10121-2 30 SummersSA