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While this is generally only a concern at extremely high doses, patients with unmanaged hypothyroidism should monitor their thyroid function when beginning supplementation

Observational Evidence for GLP-1RAs Real-world data in ARDs, particularly rheumatoid arthritis and systemic lupus erythematosus, suggest GLP-1RA use is associated with lower rates of major adverse cardiovascular events and all-cause mortality, mirroring findings in broader populations

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