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In T1DM, compounds like Irisin activate the SIRT1-p53-SLC7A11/GPX4 axis to protect -cells

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BioXCell) were administered intraperitoneally (i.p.) three times a week (every second day) for 3 weeks, at a dose of 50 g per mouse

Matos LL, Sanabria A, Robbins KT, Halmos GB, Strojan P, Ng WT, Takes RP, Angelos P, Piazza C, de Bree R, Ronen O, Guntinas-Lichius O, Eisbruch A, Zafereo ME , Mkitie AA, Shaha AR, Coca-Pelaz A, Rinaldo A, Saba NF, Cohen O, Lopez F, Rodrigo JP, Silver CE, Strandberg TE, Kowalski LP, Ferlito A