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The G-site is more hydrophilic and exhibits a higher degree of sequence conservation within GST families than the H-site [42]

Decreased GPx activity causes hepatocellular degeneration and premature death of mice

At 15 C, we observed similar results where glp-1(-) and fem-3(-) mutants lived longer and mog-3(-) mutants lived shorter than WT, although all strains had a longer lifespan at 15 C compared to 25 C, as expected (Supplementary Fig