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A pro-inflammatory state can be observed, characterized by elevated levels of cytokines such as interleukin (IL)-1, IL-6, IL-8, interferon- (IFN-), and tumor necrosis factor- (TNF-) [77]
As such, when coupled with a non-cleavable linker, the payload structure must be carefully selected and designed so that payload can exert comparable or even better anti-tumor potency in such a modified form
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Generally, this study aims to provide new regulatory targets for the development of nutritional strategies to mitigate AFB 1 -induced hepatotoxicity in chickens
En teora, estos metabolitos bacterianos podran actuar como seales que estimulan las clulas L para liberar ms GLP-1, aunque la magnitud de este efecto en humanos sigue siendo incierta
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