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While the systemic biological effects of semaglutide that indirectly benefit MASLD/MASH are robustly validated, a knowledge gap persists concerning the drug's direct effects on the liver, alongside the scientific controversy surrounding the gene and protein expression of GLP1 receptor (GLP1R) in the liver [12]

Ltude SOUL avec le semaglutide par voie orale a montr une rduction significative de 14 % du MACE chez plus de 9600 patients atteints de diabte de type 2 et de maladies cardiovasculaires ou de MRC

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