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It also leads to notable weight loss

Harvested proteins or immunoprecipitates were separated using 10% sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) then transferred to polyvinylidene difluoride (PVDF) membranes

Further research from 2024 reached a similar conclusion

Bupropion (a norepinephrine-dopamine reuptake inhibitor) stimulates pro-opiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus, leading to the release of alpha-melanocyte-stimulating hormone (-MSH), which in turn activates melanocortin receptors to reduce food intake and increase energy expenditure