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Any synergy claim should be treated as mechanistic inference rather than 2026-grade evidence [9]

The critical metabolic compound responsible for facilitating this process is carnitine, a quaternary ammonium compound biologically active in its L isoform (13, 15, 16)

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Fras JP, Auerbach P, Bajaj HS et al (2021) Efficacy and safety of once-weekly semaglutide 2.0 mg versus 1.0 mg in patients with type 2 diabetes (SUSTAIN FORTE): a double-blind, randomised, phase 3B trial