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Using click chemistry, we incorporated a biotin tag that facilitated streptavidin pulldown of proteins covalently modified by our probes, followed by quantitative mass spectrometry (MS) for target identification

Preclinically, co-administration of GIP with GLP-1 produces additive and in some measures synergistic reductions in body weight and glucose, more than either alone 25

This made him hesitant about the clinical value of creating antagonists to histamine, compounds able to block the hormone's action

When the bodily iron is overloaded, flavonoids inhibit the absorption and redistribution of iron in to some extent by chelating iron, thus reducing the iron content

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