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At this time, we continue to believe that the term upstream driver(s) is more comprehensive and includes a variety of factors that can impact the health of Medicare beneficiaries, such as smoking, poor nutrition, low physical activity, substance misuse, or potential dietary, behavioral, medical, and environmental drivers that when addressed, may lessen the impacts of ( the problem(s) addressed in the initiating visit

Full disclaimer 1.Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively stimulates GH release from the pituitary by activating the ghrelin receptor (GHSR)

Cell 26 , 44384450 (2015)