At the same time, Circana saw a relative decrease in spending during the first year of use on sleep remedies, analgesics, home healthcare products and foot care products, due to improved overall health
All adverse event data in this article comes from two sources: the Phase 2 trial published in the New England Journal of Medicine (Jastreboff et al., 2023) and the TRIUMPH Phase 3 program data presented at medical conferences
When the foot is pointed downward (plantar flexion), as it often is due to tucked bedding or heavy blankets, the calf muscles are shortened, making them more susceptible to spasms
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However, frequent stop-start cycles often lead to frustration and weight cycling, which is why most doctors recommend either continuous therapy or extended pauses with strong behavioral support
