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The FDA has also flagged BPC-157 as a bulk drug substance that may present significant safety risks when used in compounding, noting limited safety information and concerns like immunogenicity for certain routes of administration and peptide-related impurities

Research use therefore focuses on mechanism, target validation, and combinatorial experiments (e.g., with dietary change or NAD precursors) [14,8,9]

10.3389/fncel.2022.841731 72 WangY.CaoP.AlshwmiM.JiangN.XiaoZ.JiangF.et al (2019)