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Semaglutide reduced alcohol craving on average, but its effects on drinking behavior were not uniform across every measure

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Contact your provider if you experience persistent or worsening irritability that interferes with daily functioning, relationships, or quality of life

When to talk to your provider Contact your provider if you experience no appetite suppression after 4 weeks of consistent use, if side effects worsen rather than improve over time, if you develop mouth sores or persistent oral irritation, or if your results plateau significantly after previously good progress