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Another drug that hits the same receptor, dulaglutide, has also been available to treat diabetes for years

The SURMOUNT-5 head-to-head trial confirmed tirzepatide outperforms semaglutide by approximately 6 percentage points on average weight loss

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Theoretically, yes, you can take a break from Wegovy, but its unlikely to be recommended by clinicians as youd need to drop back down to the lowest dose should you decide to go back on the medication

The cells were subsequently washed with 250 l lysis buffer, incubated for 15 min with 500 l lysis buffer, and incubated for 10 min in 500 l stimulation buffer (similar to lysis buffer but with 0 or 5 mmol/l ATP and 1.65 or 6.65 mmol/l CaCl 2 ) at 37 C, 5% CO 2