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A meta-analysis of trials testing multiple GLP1RA in diabetic patients revealed that major adverse cardiovascular events, including stroke, myocardial infarction, and cardiovascular death, decreased by 12% in treated patients irrespective of the drug used or the population studied

Since then, numerous studies have been done to understand the GPx-like catalytic mechanism of ebselen and to test its potential as a therapeutic invention for preventing or treating oxidative stress-related disorders [76]