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The metabolic benefit extends beyond weight loss: studies show improved insulin sensitivity, better lipid profiles, and reduced cardiovascular risk markers in non-obese adults treated with GLP-1 agents

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In research models, GLP-1 receptor activation is associated with glucose-dependent insulin secretion, suppression of glucagon release, slowed gastric emptying, and reduced food intake through central appetite-regulating circuits

Moreover, d-allulose (1 g kg 1 ) failed to alter blood glucose levels in Glp1r KO mice (Fig

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