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Studies using human disease cell model showed that this deletion caused a significant reduction in the mitochondrial targeting ability of the NDUFV2 protein [114]

A short walk can also support digestion and blood sugar control

Exposure to mycotoxins from vegetables and fruits, such as 3-nitropropionic acid (3-NP), disrupts mitochondrial function, decreases ATP production, increases ROS, and results in spindle defects and elevated apoptosis [97]

Clinically, these insights suggest that routine metabolic profilingespecially of carnitine-acylcarnitine pathwayscould serve as a valuable adjunct in assessing treatment response and guiding individualized therapy