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Mutation Loci of the NPT1 ( SLC17A1 ) Gene The study selects 545 Japanese men with gout as a model group and 1,115 healthy men as a normal control group to investigate mutations in the NPT1 rs1165196 and I269T genes ( rs1165196 variants significantly reduce the risk of renal under excretion gout and enhance the renal urate secretion (Sakiyama et al., 2016)

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Magnetic resonance imaging (MRI) reveals a well-defined, usually homogeneous tumor exhibiting low signal intensity relative to skeletal muscle on T1-weighted images and a hyperintense appearance relative to muscle on T2-weighted images ( Fig