M204 ECL1 A and Y205 ECL1 A single mutants exhibited wild-type GLP-1 pharmacology in rat GLP-1R (Lpez de Maturana et al., 2004), but diminished GLP-1 affinity and potency in hGLP-1R in another study (Yang et al., 2016)
If your appetite remains strong and you're eating balanced meals with plenty of whole foods, you may get sufficient electrolytes from diet alone
Yu J, Sweeting AN, Gianacas C, Houston L, Lee V, Fletcher RA, et al
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