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Why DSIP Resists a Simple Dose-Response Story Most dosage articles can be written because the underlying compound behaves predictably: more drug produces more effect until a ceiling, the effect tracks the blood level, and the blood level decays on a known schedule

This reflects a broader industry reality: large pharma companies may prefer acquiring differentiated platforms rather than building from zero in an increasingly crowded race

doi: 10.1016/j.cmet.2018.05.018